ABSTRACT
Introduction: Coronavirus disease (COVID-19) is an infectious disease caused by the SARS-CoV-2 virus. Maternal physiological adaptations in pregnancy, and the physiological state of relative immune suppression, place pregnant women at increased risk of infection [1,2]. The present study is important due to the tremendous impact Covid 19 has on people at large, especially expectant mothers. In our study, we collected information on pregnant women with confirmed SARS-CoV-2 infection. Aim and Objective: 1) To estimate clinical features, maternal and perinatal outcome of Covid 19, during first, second and third wave of covid pandemic 2) To compare the Obstetric outcome in first and second wave with third wave. 3) To estimate vertical transmission to new born child in this institution as evidenced by test positivity. Method(s): Retrospective observational study was designed to examine the clinical characteristics and outcome of covid positive pregnancies admitted in our institution. Result(s): In our study of 266 pregnant women with covid, it was noticed that the mean age of the patients was found to be 27.55 years with a standard deviation of +/-4.99 years. 55.64% of cases belonged to category B1, 33.08% in B2 and 11.28% in C. 2nd wave had more patients in category C. Gestational diabetes complicated 28.95% and hypertension in 17.29% of study population. Inflammatory markers were more elevated in 2nd and 3rd wave. There was a total maternal death of 11 patients. Out of this, 10 was (91%) due to covid pneumonia and ARDS. Breast feeding was given for 88.7% of the babies and for 88% of the babies rooming in was practiced. Only 2.6% of the babies turned positive within a week. Conclusion(s): Our study shows that expectant mothers were more severely affected in the second wave. Maternal mortality was associated with increased maternal age (> 35 years), raised CRP levels (> 75mg/L) and higher D dimer levels (> 3000 ng/ml) and is found to be statistically significant. There is no evidence to show any vertical transmission of the disease as only 2.1% of the neonates (7nos) were affected within a week. Copyright © 2022, Dr Yashwant Research Labs Pvt Ltd. All rights reserved.